No, you most likely wont take Injectafer long term. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. But if they become more severe or dont go away, talk with your doctor or pharmacist. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. And this can affect how well those parts of your body are able to work. You may report side effects to the FDA at 1-800-332-1088. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Talk to your pharmacist for more details. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). This site is intended for use only by US patients. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. intense abdominal pain. (See also Notes section.). Call your doctor for medical advice about side effects. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. Side Effects of Venofer (Iron Sucrose Injection), Warnings, Uses - RxList Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Possibleside effectsareweight gainand suicidal thoughts. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. chest pain. You may need extra iron because of blood loss during kidney dialysis. I had my first infusion of 1gm 10 days ago. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. (Hemoglobin is a protein thats found inside your red blood cells.). Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. However, diarrhea it isnt very common in people using Injectafer. Best food forward: Are algae the future of sustainable nutrition? Consult your doctor before breast-feeding. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. 4 0 obj (One treatment course includes two doses of the drug.) There may be risks to the mother and fetus associated with untreated IDA in pregnancy. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. The infusion will take between 15-30 minutes if it is given in. Nose or throat irritation. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. experience severe side effects, please seek medical attention right away and notify the ordering physician. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. How Long Do Side Effects Last | Education Center - Sequencing And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. Diarrhea. But its not known whether this poses any risk to a child whos breastfed. They can tell you about other medications that may work well for you. As with most drugs, some people can have an allergic reaction after taking Injectafer. Details. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. Injectafer and Feraheme are both brand-name drugs. Iron sucrose can also be mixed in a. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. For more information about Injectafers approved uses, see the section Injectafer uses below. Low iron saturation, or iron deficiency, has various possible causes. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. This is not a complete list of side effects and others may occur. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. What Is the Cost of Whole Genome Sequencing (WGS)? How long does iron infusion stay in your system? Allergic reactions typically occur the first time your body is exposed to a drug. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. What to Know About Iron Infusions for Anemia Treatment - GoodRx Your doctor will do laboratory tests to monitor your response. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Side effectsare uncomfortable reactions to medications or drugs. Hes an expert in genetic testing, genetic analysis, andprecision medicine. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. PDF Venofer - Food and Drug Administration There are different types of anemia, but IDA is the most common type. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. Some products that may interact with this drug include: vitamin products, other iron-containing products. It belongs to a class of medications called iron replacement products. There are 2 tests that your doctor will likely Do not start, stop, or change the dose of any drug without checking with your doctor. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Theyll recommend how to manage your condition. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. Copyright 1996-2023 Cerner Multum, Inc. These are not all of the side effects that may occur. fever. Injectafer helps to treat IDA by providing an iron infusion directly into your body. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. Injectafer (ferric carboxymaltose): Side effects and more Injectafer and Venofer are both brand-name drugs. This test measures the amount of hemoglobin in your blood. Venofer pregnancy and breastfeeding warnings. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Iron infusion: Uses, benefits, and what to expect - Medical News Today Talk with the doctor. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. endobj You may report side effects to the FDA at 1-800-332-1088. VenAccess is a trademark of Vifor (International) Inc. Switzerland. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 1 0 obj Yes, in some cases it may. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Talk with your doctor. Otherwise, call a poison control center right away. And this could lead to weight gain, if they increase their food intake. Evenbirth controlcan lead to severeside effectslike bloodclots. Common and Rare Side Effects for Venofer Vial - WebMD Phosphorus also helps your nerves function properly. Venofer may reduce the absorption of iron preparations taken by mouth. However, side effects at the 150 mg dose may indicate that you might not . These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). People with IDA have low blood levels of hemoglobin. Some people only need one treatment course of Injectafer. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. 2005 - 2023 WebMD LLC. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Its given by either intravenous (IV) infusion or slow IV injection. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. 3 0 obj Below are examples of these side effects. xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? Check with your pharmacist if you have questions about the best way to throw out drugs. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. Discuss the risks and benefits with your doctor. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Weight changes may be due to symptoms of anemia improving. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. We cancelled my 5th because of the reaction. During Injectafer treatment, your doctor will likely order blood tests. It is important to get each dose of this medication as scheduled. treatment schedule in further detail. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. Serious side effects should be reported to a physician and/or PharmD for medical advice. With slow IV injection, the drug is given as a single, slow injection into your vein. Have blood work checked as you have been told by the doctor. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. Venofer may cause significant hypotension (decreased blood pressure). Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Sharing this information can help you avoid potential interactions. SIDE EFFECTS: In adult patients, the most common side effects (2%) include diarrhea, upset stomach, throwing up, headache, dizziness, hypotension, pruritus (itching), pain in extremity, arthralgia (joint pain), back pain, muscle cramp, injection site reactions, chest pain and peripheral edema (swelling). Consult the product instructions and your pharmacist for storage details. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. 2023 Medicine.com All rights reserved. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Injectafer can cause mild or serious side effects. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). Depending on your anemia symptoms, your weight changes may be different than those described here. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Is the ketogenic diet right for autoimmune conditions? He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). So we cant say for sure whether the drug is safe to use while youre pregnant. In one study, people were given either Injectafer or an iron replacement drug called Venofer. 2 0 obj But for other people, their IDA returns after treatment with Injectafer. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. Call your doctor for medical advice about side effects. Here we look at how Injectafer and Feraheme are alike and different. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. In clinical trials,. For people with certain medical implants, such as pacemakers, an MRI may pose an . Their medical staff can help you set up another time to receive your Injectafer dose. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. % If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. Venofer is given as an infusion into a vein. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. A variety of tests can diagnose iron deficiency anemia. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. We comply with the HONcode standard for trustworthy health information. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. And this can lead to anemia, including IDA. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. This is not a list of all drugs or health problems that interact with this medicine. This medication is given by injection into a vein as directed by your doctor.
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